The clip for the zombie apocalypse series shows "the walkers" encroaching on the survivors at their prison enclave.
"Yeah, the walkers are no threat at all this season," executive producer Gale Anne Hurd jokingly told the crowd.
The clip also teased a catastrophic event inside the prison with multiple deaths. At the end of the trailer, Norman Reedus' Daryl is shown driving a car and overhearing a voice on the radio whispering, "Those who arrive survive."
The upcoming season will premiere Oct. 13.