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The first trailer for "Dallas Buyers Club" debuted on Tuesday, featuring a very lethargic Matthew McConaughey.

The 43-year-old actor plays the starring role of Ron Woodroof, a Texas man who began smuggling non-approved drugs into the U.S. after learning he's HIV-positive.

Getting fit for the character wasn't easy for McConaughey, who lost nearly 50 pounds in preparation for the film.

"Dallas Buyers Club" co-stars Jennifer Garner and Jared Leto and will open in theaters Nov. 1.,

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