"We still have time," Whisenhunt told reporters. "But, it doesn't look good for John [Skelton] being able to play."

Skelton, who was named the team's starting quarterback just two weeks ago, suffered a low ankle sprain after completing a 4th quarter pass in the Cardinals' 20-16 win over the Seahawks in Week 1.

"He's getting better," said Whisenhunt on Skelton's status. "He did some work today and a little bit with the rehab stuff. So, he is improving."

After being taken off the field in a cart, Skelton was replaced by back-up quarterback Kevin Kolb, who promptly drove the Cardinals down the field and threw the eventual game-winning touchdown pass to Andre Roberts. On the day, Kolb finished with 66 yards on 6-of-8 passing.

Last season, Kolb began the year as the team's starting quarterback, but a litany of injuries and poor play cut his season short. In just nine games, he threw for 1,955 yards with 9 TD and 8 INT. Before last Sunday's late-game heroics, Kolb hadn't played in a regular season game since Dec. 4 against the 49ers.

"Kevin had a very good week of practice and he played well[against the Seahawks]," said Whisenhunt.

If Kolb does get the start against the reigning AFC champions, it would be just the 17th time in his six-year career.

Arizona Sports' Craig Grialou contributed to this report