It wasn't so much the big inning that did in Arizona Diamondbacks left-hander Wade Miley Sunday.
No, unlike his rotation brethren Brandon McCarthy, it was the big fly that sealed Miley's fate in the final game of the D-backs' four-game set with the Cincinnati Reds at Chase Field.
Coming off a career-high, 11-strikeout performance, Miley set a new personal high, although not of the positive variety.
Cincinnati combined to club four solo shots off of Miley over his six innings of work, and even a big three-run fourth inning was not enough to pull Arizona ahead on the afternoon.
Reds right-hander Alfredo Simon pitched 6.1 innings of quality baseball, as the Reds recorded their third consecutive win in the Valley, 4-3.
Here's a look back at the one-run loss by the numbers:
After Sunday's defeat, Arizona falls to 0-4 in the first home game of each month: March 31 vs. Giants, April 1 vs. Giants, May 12 vs. Nationals and June 1 vs. Reds.
David Peralta was called up from Double-A Mobile Sunday to fill A.J. Pollock's spot on the 25-man roster. In his major league debut, Peralta went 2-for-4 with a run scored.
He became just the sixth D-back to ever record two or more hits in his debut. The others were Mark Reynolds, Trent Oeltjen, Adam Eaton, Chris Snyder and Travis Lee.
Outside of the Pittsburgh Pirates, the D-backs have already played against every team in the National League Central. That hasn't exactly been a good thing, either.
In 14 games against the NL Central, Arizona is an unimpressive 5-9 (.357 winning percentage).
Even in a losing effort, Arizona made a little bit of history as each of its five Venezuelan-born starters -- Ender Inciarte, Peralta, Gerardo Parra, Martin Prado and Miguel Montero -- recorded at least one base hit.
Reliever Oliver Perez's scoreless streak was extended to nine appearances despite a topsy-turvy top half of the ninth. Perez allowed two hits and walked a batter before being replaced by Addison Reed, who retired the final two Reds he faced.
The veteran left-hander hasn't yielded a run since May 4.
For the 13th consecutive game, D-backs first baseman Paul Goldschmidt was retired at least once via the strikeout. In 2013, Goldschmidt never have a streak longer than seven games.
Miley has now given up 14 long balls in 13 starts this season -- the second-most by any pitcher in all of baseball.
In his last two outings, Miley has combined to punch out 20 batters, including nine on Sunday. The 20 strikeouts over a two-game stretch is a new career-high surpassing the 16 he recorded in June 2012 against the Seattle Mariners and Texas Rangers.
Since 1914, only four pitchers have had nine or more strikeouts, allowed four or more home runs and walked zero in the same game. Miley became the fifth Sunday.
The last D-backs pitcher to give up four runs all on solo home runs was Dan Haren against the Toronto Blue Jays in May 2010. That night, Arizona fell by a final of 8-6.