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Tyrann Mathieu, Cardinals DB depth takes hit vs. Panthers

Carolina Panthers' Kelvin Benjamin (13) runs after a catch as Arizona Cardinals' Tyrann Mathieu (32) and Patrick Peterson (21) defend in the first quarter of an NFL football game in Charlotte, N.C., Sunday, Oct. 30, 2016. (AP Photo/Bob Leverone)

Cardinals safety Tyrann Mathieu went down with a shoulder injury in the first half of Arizona’s visit to the home of the Carolina Panthers and was listed as probable to return.

Mathieu, however, was still not on the field as the Cardinals came out of the halftime break.

Arizona ruled him out for the game in the third quarter.

Tharold Simon replaced Mathieu at his slot cover spot but he went down with an injury in the third quarter and went to the locker room. The team said he was questionable to return with an ankle injury.

Cornerback Marcus Cooper moved into the slot from his corner position, and special teamer and backup corner Justin Bethel entered to defend on the outside opposite Patrick Peterson.

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