ARIZONA CARDINALS

D.J. Humphries reportedly sprains knee, could miss multiple weeks

Sep 10, 2017, 10:43 AM | Updated: 3:14 pm

(AP Photo/Ross D. Franklin)...

(AP Photo/Ross D. Franklin)

(AP Photo/Ross D. Franklin)

Arizona Cardinals starting left tackle D.J. Humphries left the Week 1 game against the Detroit Lions with a knee injury and did not return.

It was reported after the game by NFL Network’s Ian Rapoport that Humphries could miss a few weeks because of a right knee sprain, pending an MRI.

FOX sideline reporter Laura Okmin reported that Humphries went to the locker room after he was injured.

Backup offensive lineman John Wetzel replaced Humphries.

Already one of the Cardinals’ biggest question marks heading into 2017, the offensive line also started a banged up Mike Iupati, who was limited in practices heading into Sunday. He started at left guard.

While Arizona’s pass protection held up adequately through most of the first quarter of three offensive possessions, it struggled to open holes for running back David Johnson.

The third-year pro had seven carries and only nine yards through the first three Cardinals possessions.

Detroit Lions wide receiver Golden Tate wears cleats adorned with a remembrance of the 9/11 terrorist attacks on the World Trade Center in New York during an NFL football game against the Arizona Cardinals in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Paul Sancya) Detroit Lions strong safety Tavon Wilson intercepts an Arizona Cardinals quarterback Carson Palmer pass during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Duane Burleson) Arizona Cardinals cornerback Justin Bethel (28) breaks a tackle after intercepting a Detroit Lions quarterback Matthew Stafford pass for an 82-yard touchdown during the first quarter of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions wide receiver Golden Tate wears cleats adorned with a remembrance of the 9/11 terrorist attacks on the World Trade Center in New York during an NFL football game against the Arizona Cardinals in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Paul Sancya) Arizona Cardinals cornerback Justin Bethel (28) celebrates with strong safety Antoine Bethea (41) after intercepting a Detroit Lions quarterback Matthew Stafford pass for an 82-yard touchdown during the first quarter of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions wide receiver Golden Tate wears cleats adorned with a remembrance of the 9/11 terrorist attacks on the World Trade Center in New York during an NFL football game against the Arizona Cardinals in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Paul Sancya) Detroit Lions defensive tackle Anthony Zettel (69) stops Arizona Cardinals running back David Johnson (31) during an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions wide receiver Golden Tate wears cleats adorned with a remembrance of the 9/11 terrorist attacks on the World Trade Center in New York during an NFL football game against the Arizona Cardinals in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Paul Sancya) Arizona Cardinals quarterback Carson Palmer (3) hands off to running back David Johnson (31) against the Detroit Lions during an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions free safety Glover Quin, right, tackles Arizona Cardinals running back David Johnson (31) during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions quarterback Matthew Stafford (9) throws against the Arizona Cardinals during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Protesters rally for former quarterback Colin Kaepernick outside Ford Field and an NFL football game between the Detroit Lions and the Arizona Cardinals in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Protesters march in support of former quarterback Colin Kaepernick outside Ford Field and an NFL football game between the Detroit Lions and the Arizona Cardinals in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions punter Kasey Redfern (2) runs the ball out of the end zone as Arizona Cardinals running back Elijhaa Penny (35) pursues during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals outside linebacker Chandler Jones (55) sacks Detroit Lions quarterback Matthew Stafford (9) during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions running back Ameer Abdullah (21) runs past the reach of Arizona Cardinals outside linebacker Chandler Jones, left, during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals cornerback Justin Bethel (28) celebrates his 82-yard interception for a touchdown with Patrick Peterson (21) during the first half of an NFL football game against the Detroit Lions in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals defensive back Tyvon Branch (27) tackles Detroit Lions quarterback Matthew Stafford (9) on a run during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions wide receiver Golden Tate (15) is brought down by Arizona Cardinals defensive back Tyvon Branch (27) as Antoine Bethea (41) looks on during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals linebacker Haason Reddick (43) tackles Detroit Lions running back Ameer Abdullah (21) during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions wide receiver Marvin Jones (11) catches a 6-yard touchdown as Arizona Cardinals cornerback Patrick Peterson (21) defends during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Detroit Lions running back Theo Riddick (25) breaks the tackle of Arizona Cardinals linebacker Karlos Dansby (56) during the first half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals running back Kerwynn Williams (33) runs for a 3-yard touchdown against the Detroit Lions during the second half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals running back David Johnson (31) is injured against the Detroit Lions during the second half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. Johnson left the field for x-rays. (AP Photo/Jose Juarez) Arizona Cardinals running back Kerwynn Williams (33) reacts with Evan Boehm (70) after scoring a 3-yard touchdown against the Detroit Lions during the second half of an NFL football game in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez) Arizona Cardinals running back David Johnson (31) walks off the field with medical staff for X-rays during an NFL football game against the Detroit Lions in Detroit, Sunday, Sept. 10, 2017. (AP Photo/Jose Juarez)

Arizona Cardinals

Zaven Collins during OTAs...

Tyler Drake

Cardinals LB Zaven Collins embracing life on the edge

Cardinals linebacker Zaven Collins is getting more work on the outside than ever before since arriving to the desert in 2020.

19 hours ago

Colt McCoy...

Tyler Drake

Colt McCoy, Cardinals experiencing the ‘learning curve’ of new regime

Cardinals quarterback Colt McCoy sees the value in organized team activity reps, especially working under a new OC and offensive scheme.

19 hours ago

Bobby Price #27 of the Detroit Lions celebrates the stop of a punt return during the second half ag...

Arizona Sports

Arizona Cardinals sign CBs Bobby Price, Dylan Mabin

The Arizona Cardinals added a pair of cornerbacks on Monday, announcing the signings of Bobby Price and Dylan Mabin. 

19 hours ago

Larry Fitzgerald, Pittsburgh Panthers, college football...

Arizona Sports

Larry Fitzgerald, 3 ASU players on 2024 College Football Hall of Fame ballot

Former Arizona Cardinals great Larry Fitzgerald and three Arizona State Sun Devils are on the 2024 College Football Hall of Fame ballot.

19 hours ago

Dallas Goedert #88 of the Philadelphia Eagles jumps out of a tackle by Dennis Gardeck #45 of the Ar...

Alex Weiner

Cardinals OLB Dennis Gardeck working to improve pass rush technique this offseason

Cardinals edge rusher Dennis Gardeck said he is improving his technique with new OLBs coach Rob Rodriguez to become a more complete rusher.

2 days ago

Kyler Murray #1 of the Arizona Cardinals warms up prior to his game against the Philadelphia Eagles...

Tom Kuebel

Bleacher Report: Cardinals’ Kyler Murray is NFL’s most overrated QB

Bleacher Report's Gary Davenport ranks Cardinals quarterback Kyler Murray as the most overrated player at his position in the NFL.

2 days ago

D.J. Humphries reportedly sprains knee, could miss multiple weeks