ARIZONA CARDINALS

Cardinals-49ers injury report: Jimmy Garoppolo ruled out Sunday

Oct 8, 2021, 1:49 PM | Updated: 1:52 pm

San Francisco 49ers starting quarterback Jimmy Garoppolo has been officially ruled out of the team’s Week 5 matchup with the Arizona Cardinals.

Garoppolo missed the entire week of practice with a calf injury suffered last Sunday.

With Garoppolo sidelined, rookie quarterback Trey Lance will make his first NFL start.

Additionally, 49ers tight end George Kittle is doubtful with a calf injury.

As for the Cardinals, cornerback Byron Murphy missed practice for the third straight day with a ribs injury and is officially out. Offensive lineman Justin Murray was also ruled out and placed on the injured reserve with a back injury.

Additionally, rookie corner Marco Wilson, running back Chase Edmonds, tight end Maxx Williams, running back Eno Benjamin, right tackle Kelvin Beachum and cornerback Antonio Hamilton are questionable.

Edmonds was present for the open portion of practice Friday after a shoulder injury kept him out Thursday.

A look at the official injury report for Week 5:

Player Position Injury Wednesday Thursday Friday Game Status
James Conner RB NIR-Personal DNP
Chase Edmonds RB Shoulder DNP DNP Limited Questionable
Antonio Hamilton CB Ankle DNP Limited Limited Questionable
DeAndre Hopkins WR NIR-Rest DNP
Rodney Hudson C NIR-Rest DNP
Chandler Jones OLB NIR-Rest DNP
Byron Murphy CB Ribs DNP DNP DNP Out
Corey Peters NT NIR-Rest DNP
Justin Pugh LG Hip DNP Limited Full
Maxx Williams TE Shoulder DNP Limited Limited Questionable
Kelvin Beachum RT Ribs Limited Limited Limited Questionable
Eno Benjamin RB Hamstring Limited Limited Limited Questionable
A.J. Green WR NIR-Rest Limited
Justin Murray OL Back Limited DNP DNP Out
Dennis Gardeck OLB Hand Full Full Full
Marco Wilson CB Ribs Full Limited DNP Questionable

Player Position Injury Wednesday Thursday Friday Game Status
Arik Armstead DE NIR-Rest DNP Full
Samson Ebukam DE Hamstring DNP DNP Limited Questionable
Jimmy Garoppolo QB Calf DNP DNP DNP Out
D.J. Jones DT Knee DNP Full
George Kittle TE Calf DNP DNP DNP Doubtful
Alex Mack C NIR-Rest DNP Full Full
K’Waun Williams CB Calf DNP DNP DNP Out
Trent Williams LT Shoulder DNP Full Full
Javon Kinlaw DT Knee Limited Limited Limited Questionable
Elijah Mitchell RB Shoulder Limited Limited Full
Josh Norman CB Chest Limited Limited Full

Arizona Cardinals

Arizona Cardinals' Kyler Murray (1) participates during the team's NFL football practice, Wednesday...
Nikash Nath

Cardinals’ Kyler Murray among top 5 QBs in multiple PFF passing metrics

Arizona Cardinals quarterback Kyler Murray's accuracy was on point in 2021, especially when looking at deep throws.
2 days ago
Arizona Cardinals linebacker Isaiah Simmons #9 during the NFL game between the Arizona Cardinals an...
Nikash Nath

PFF’s Renner: Cardinals’ Isaiah Simmons a breakout candidate in Year 3

Cardinals' inside linebacker Isaiah Simmons was named a potential year three breakout candidate by PFF's Michael Renner.
1 day ago
Rodney Hudson #61 of the Arizona Cardinals in the huddle during the game against the Tennessee Tita...
Wills Rice

Former Cardinals C A.Q. Shipley thinks offense needs to find identity

"For (Kyler) the next step is just grabbing everyone around him, whether he just needs one play and everyone will look to him," Shipley said.
2 days ago
General Manager Steve Keim of the Arizona Cardinals looks on prior to the game against the Baltimor...
Tyler Drake

Important NFL dates to remember and how they impact Arizona Cardinals

A look at the important league dates to circle on your calendar and how they relate to the Arizona Cardinals' roster decisions.
2 days ago
Arizona Cardinals head coach Kliff Kingsbury takes notes as he watches players taking part in drill...
Tyler Drake

Looming questions for the Arizona Cardinals ahead of training camp

There are quite a few questions marks surrounding the Arizona Cardinals ahead of training camp this offseason.
2 days ago
(Twitter photo/New England Patriots)...
Wills Rice

New England Patriots bring back red uniforms in Back to the Future spoof

The New England Patriots announced the team is bringing back their old-school red uniform and helmet combo for the 2022 season.
3 days ago
Cardinals-49ers injury report: Jimmy Garoppolo ruled out Sunday