ARIZONA CARDINALS

Arizona Cardinals given odds of slight favorites vs. Seahawks

Oct 15, 2022, 8:15 AM

Kyler Murray, Cardinals QB...

Kyler Murray #1 of the Arizona Cardinals runs the ball in front of Jordyn Brooks #56 of the Seattle Seahawks during the second quarter at State Farm Stadium on January 09, 2022 in Glendale, Arizona. (Photo by Norm Hall/Getty Images)

(Photo by Norm Hall/Getty Images)

The Arizona Cardinals head into Seattle for their second NFC West matchup of the 2022 season, and the oddsmakers have the Cardinals as the favorite against the Seahawks.

The spread for Arizona sits at -2.5 as of Friday, per Fan Duel Sportsbook.

This is a notable number, because for the first time all season, the Cardinals are favored. Arizona was given at least five points against the Philadelphia Eagles (+5.5), Las Vegas Raiders (+5.5) and Kansas City Chiefs (+6). It was also a +3.5 line for the Cardinals against the Los Angeles Rams, and two weeks ago, Arizona closed at +1 prior to beating the Carolina Panthers.

The Cardinals are 3-2 against the spread this year, and despite four out of five of the team’s over/unders hitting under, it’s another high bar for Week 6.

An over/under of 50.5 is the second-highest mark in Week 6, a nod to a great season for Seahawks quarterback Geno Smith thus far and a not so great season for the Seattle defense thus far.

In the props department, a fun one is the Cardinals being favored -130 in the first quarter, even though they have not scored a point in the opening 15 minutes all season.

Arizona Cardinals

Arizona Cardinals QB Kyler Murray warms up...

Tyler Drake

Predicting the Arizona Cardinals’ 2024 record

Before the Arizona Cardinals open up the regular season against the Buffalo Bills on Sunday, it's time for one last record prediction for 2024.

12 hours ago

Kyler Murray attempts a pass during Day 1 of joint practices with the Colts...

Dan Bickley

Kyler Murray has entered his now-or-never season with Cardinals

Kyler Murray's time to turn into a star is now or never for the Arizona Cardinals.

14 hours ago

Xavier Weaver is on the Week 1 Arizona Cardinals injury report...

Arizona Sports

Arizona Cardinals injury report: Rookie WR Xavier Weaver out vs. Bills

Xavier Weaver, Tip Reiman and Joey Blount are the only players listed on the Arizona Cardinals injury report for a game against the Buffalo Bills.

15 hours ago

Budda Baker of the Arizona Cardinals is entering a contract season...

Kevin Zimmerman

GM: Arizona Cardinals contract extension talks don’t stop at start of the season

Arizona Cardinals general manager Monti Ossenfort believes that the start of the 2024 season does not always represent a hard deadline to reach contract extensions with his currently employed players.

19 hours ago

Arizona Cardinals quarterback Kyler Murray...

Arizona Sports

Roundtable: The Arizona Cardinals’ best- and worst-case scenarios for 2024

The Arizona Cardinals have reasons to be optimistic about taking a leap from a four-win debut season for the Gannon era.

23 hours ago

Quarterback Josh Allen #17 of the Buffalo Bills drops back to pass during the NFL game against the ...

Tyler Drake

Bills to watch in Cardinals’ Week 1 game vs. Buffalo

There are plenty of Buffalo Bills that could have major impacts in their Week 1 season opener against the Arizona Cardinals.

2 days ago

Arizona Cardinals given odds of slight favorites vs. Seahawks