Cardinals’ Kyler Murray placed on injured reserve with foot injury

TEMPE — The Arizona Cardinals are placing quarterback Kyler Murray on injured reserve with his foot injury, head coach Jonathan Gannon announced Wednesday.

The news comes after Gannon named Jacoby Brissett the Cardinals’ starting quarterback a day prior, citing the offense’s noticeable improvement and Murray’s health status as the primary reasons behind the move.

Jonathan Gannon said the pivot to place Kyler Murray on IR “is completely predicated on the information that we have now and his health. He’s got to fully focus on getting healthy.” pic.twitter.com/x6z0YaJuxg

— Tyler Drake (@Tdrake4sports) November 5, 2025

“This pivot, I would say, is completely predicated on the information that we have now and his health,” Gannon said. “He’s got to fully focus on getting healthy. He’s in a good spot and ready to do that.”

Murray, who has already missed three games with the foot injury suffered in Week 5’s loss to Tennessee, now must miss the next four games:

– At Seattle
– Vs. San Francisco
– Vs. Jacksonville
– At Tampa Bay

The earliest he could return is Week 14 against the Los Angeles Rams.

“He wants to play football,” Gannon said when asked how Murray took the IR decision. “I laugh with him. He likes to be at recess not in the classroom. Recess for him is on the grass.

“Not to say he doesn’t like the classroom, … he’s phenomenal in the meeting room. If you ask him, ‘What’s your favorite thing to do?’ it’s probably be on the grass and play football, so that’s hard for him. But he understands.”

Murray’s time on the shelf could extend beyond that stretch, however.

According to ESPN’s Adam Schefter, Murray’s foot injury has a recovery timeline of four to eight weeks. Schefter adds there is an increased chance at reaggravating the injury.

But even if Murray was healthy, Brissett had more than earned the right to start another game.

In the veteran’s three fill-in performances, Brissett completed 65.7% of his throws for 860 yards and six touchdowns to one interception. He’s also ran the rock 14 carries for 49 yards and a touchdown.

Arizona also released offensive lineman Nick Leverett from its practice squad on Wednesday.

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