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ARIZONA CARDINALS INJURY REPORT

Cardinals-49ers injury report: Nick Bosa reportedly out for NFC West battle

The Arizona Cardinals will get the benefit of not having to face Nick Bosa, but they still enter their Week 4 matchup with the San Francisco 49ers shorthanded in the secondary.

Cardinals' Week 3 injury report...

GLENDALE, ARIZONA - NOVEMBER 23: Garrett Williams #21 of the Arizona Cardinals celebrates his third quarter interception against the Jacksonville Jaguars at State Farm Stadium on November 23, 2025 in Glendale, Arizona. The Jaguars defeated the Cardinals 27-24 in overtime. (Photo by Chris Coduto/Getty Images)

(Photo by Chris Coduto/Getty Images)

The Arizona Cardinals will not have to face star pass rusher Nick Bosa in Sunday’s NFC West matchup with the San Francisco 49ers, ESPN’s Adam Schefter reported Friday.

That was after Arizona listed cornerbacks Max Melton and Garrett Williams on the matchup’s injury report Thursday.

Melton returned to practice after being a non-participant on Wednesday with a toe issue. Williams remained limited on Thursday.

Williams has yet to make his season debut after sustaining a torn Achilles tendon last year. Melton left the Sept. 20 game against the Seattle Seahawks with the toe injury.

Safety Dadrion Taylor-Demerson (ribs) returned to practice on Thursday as a limited participant after not practicing on Wednesday.

The Cardinals’ secondary has dealt with tough injury news this week after cornerback Will Johnson was placed on injured reserve with a potentially season-ending neck injury.

Quarterback Jacoby Brissett remained on the injury report with a hip issue, but he was a full participant for the second consecutive day.

While Arizona’s secondary is reeling, San Francisco’s receiving corps is having its own injury problems.

Receivers De’Zhaun Stribling, Ricky Pearsall and Christian Kirk are already on injured reserve, while Mike Evans and Demarcus Robinson did not practice on Thursday.

Here is the latest injury report for the Cardinals’ Week 3 game against the 49ers:

Cardinals-49ers Week 3 injury report

Arizona Cardinals
Player Pos Injury Wednesday Thursday Friday Game Status
Isaac Seumalo OL NIR-Rest DNP Full
Josh Sweat LB NIR-Rest DNP Full
Roy Lopez DL Groin DNP DNP
Max Melton CB Toe DNP Limited
Dadrion Taylor-Demerson S Back DNP Limited
Garrett Williams CB Achilles Limited Limited
Hjalte Froholdt OL Knee Limited Limited
Mack Wilson Sr. LB NIR-Rest/Thumb Limited Full
Jacoby Brissett QB Hip Full Full

San Francisco 49ers
Player Pos Injury Wednesday Thursday Friday Game Status
Nick Bosa DE NIR-Rest/Knee DNP DNP
Mike Evans WR Hip DNP DNP
Dre Greenlaw LB NIR-Rest/Achilles DNP Full
Romello Height DE Hand DNP DNP
Christian McCaffrey RB NIR-Rest DNP Full
Demarcus Robinson WR Ankle DNP DNP
James Thompson DT Ankle DNP DNP
Trent Williams T NIR-Rest DNP Full

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