ARIZONA CARDINALS INJURY REPORT
Cardinals-49ers injury report: Nick Bosa out, Garrett Williams on track for season debut
Garrett Williams returns to the Cardinals lineup at a key moment, as they just lost starting cornerback Will Johnson for potentially the entire season.
GLENDALE, ARIZONA - NOVEMBER 23: Garrett Williams #21 of the Arizona Cardinals celebrates his third quarter interception against the Jacksonville Jaguars at State Farm Stadium on November 23, 2025 in Glendale, Arizona. The Jaguars defeated the Cardinals 27-24 in overtime. (Photo by Chris Coduto/Getty Images)
(Photo by Chris Coduto/Getty Images)
The Arizona Cardinals will not have to face star pass rusher Nick Bosa in Sunday’s NFC West matchup with San Francisco, as he was among four 49ers ruled out.
Arizona will be without safety Dadrion “Rabbit” Taylor-Demerson while defensive lineman Roy Lopez and cornerback Max Melton are both questionable.
One notable Cardinal without an injury designation for Sunday was cornerback Garrett Williams, who saw full participation in practice for the first time this season on Friday. He is on track to make his season debut after tearing his Achilles last December.
Getting Williams back is huge for a Cardinals secondary that was dealt tough injury news this week as cornerback Will Johnson was placed on injured reserve with a potentially season-ending neck injury.
Quarterback Jacoby Brissett remained on the injury report with a hip issue, but he was a full participant in all three days of practice.
While Arizona’s secondary is reeling, San Francisco’s receiving corps is having its own injury problems.
Receivers De’Zhaun Stribling, Ricky Pearsall and Christian Kirk are already on injured reserve, while Mike Evans is questionable and Demarcus Robinson was ruled out for Sunday.
Here is the final injury report for the Cardinals’ Week 3 game against the 49ers:
Cardinals-49ers Week 3 injury report
| Arizona Cardinals | ||||||
|---|---|---|---|---|---|---|
| Player | Pos | Injury | Wednesday | Thursday | Friday | Game Status |
| Isaac Seumalo | OL | NIR-Rest | DNP | Full | — | — |
| Josh Sweat | LB | NIR-Rest | DNP | Full | — | — |
| Roy Lopez | DL | Groin | DNP | DNP | Limited | Questionable |
| Max Melton | CB | Toe | DNP | Limited | Limited | Questionable |
| Dadrion Taylor-Demerson | S | Back | DNP | Limited | DNP | Out |
| Garrett Williams | CB | Achilles | Limited | Limited | Full | — |
| Hjalte Froholdt | OL | Knee | Limited | Limited | Full | — |
| Mack Wilson Sr. | LB | NIR-Rest/Thumb | Limited | Full | Full | — |
| Jacoby Brissett | QB | Hip | Full | Full | Full | — |
| San Francisco 49ers | ||||||
|---|---|---|---|---|---|---|
| Player | Pos | Injury | Wednesday | Thursday | Friday | Game Status |
| Nick Bosa | DE | NIR-Rest/Knee | DNP | DNP | DNP | Out |
| Mike Evans | WR | Hip | DNP | DNP | Limited | Questionable |
| Dre Greenlaw | LB | NIR-Rest/Achilles | DNP | Full | Full | — |
| Romello Height | DE | Hand | DNP | DNP | DNP | Out |
| Christian McCaffrey | RB | NIR-Rest | DNP | Full | Full | — |
| Demarcus Robinson | WR | Ankle | DNP | DNP | DNP | Out |
| James Thompson | DT | Ankle | DNP | DNP | DNP | Out |
| Trent Williams | T | NIR-Rest | DNP | Full | Full | — |
Related
Cardinals-Rams Week 6 injury report: Jeremiyah Love still not participating at practice Thursday
Cardinals-Lions Week 5 injury report: Jeremiyah Love good to go, Walter Nolen III questionable
Cardinals-Giants injury report: Josh Sweat questionable with groin issue
Cardinals-Seahawks injury report: Garrett Williams ruled out, Melton among 6 questionable
Cardinals-Chargers injury report: Jeremiyah Love expected to play in Week 1
Cardinals-Rams injury report: Marvin Harrison Jr. lands on IR
Comments
5 Comments
His slow start was predictable after doing nothing all summer. I think he will be better in the coming weeks hopefully this week. 49ers iOL isn’t good, hopefully Walter Nolen has a huge game this weekend to .
this is a winnable game, hopefully they show up ready to prove a point after the egg they laid last sunday
I think he will be better in coming weeks hopefully starting this week. Sweats slow start to the season was foreseeable after not doing shite all thru camp, he’s not going to purposely sabotage his market though that only hurts his bottom line and affects his ability to get paid on the open market after this season.
San Francisco’s OL isn’t all that great and their interior OL sucks. Hopefully Sweat and Walter Nolen wreck this weekend , I think this week Walter Nolen is going to wreck their interior and have himself a game, I think he has a big day on Sunday to the tune of 1-2 sacks and a handful of pressures.
This is a very winnable game for the Cardinals, so long as they show up and play to their ability AZ should win. SF will have no pass rush and their run defense isn’t good, Brissett should have clean pockets and Love/Allgeier should go off in this game. Sucks to Lose Will Johnson but with Garrett Williams back it’s not a huge loss given the depth at corner. Arizona just needs to get the run going and all these guys play makers they have at receiver/tight end need to actually make plays this week. Looking at SFs roster though AZ should win so long as they show up.
AZ wins this one 27-23