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ARIZONA CARDINALS INJURY REPORT

Cardinals-49ers injury report: Nick Bosa out, Garrett Williams on track for season debut

Garrett Williams returns to the Cardinals lineup at a key moment, as they just lost starting cornerback Will Johnson for potentially the entire season.

Cardinals' Week 3 injury report...

GLENDALE, ARIZONA - NOVEMBER 23: Garrett Williams #21 of the Arizona Cardinals celebrates his third quarter interception against the Jacksonville Jaguars at State Farm Stadium on November 23, 2025 in Glendale, Arizona. The Jaguars defeated the Cardinals 27-24 in overtime. (Photo by Chris Coduto/Getty Images)

(Photo by Chris Coduto/Getty Images)

The Arizona Cardinals will not have to face star pass rusher Nick Bosa in Sunday’s NFC West matchup with San Francisco, as he was among four 49ers ruled out.

Arizona will be without safety Dadrion “Rabbit” Taylor-Demerson while defensive lineman Roy Lopez and cornerback Max Melton are both questionable.

One notable Cardinal without an injury designation for Sunday was cornerback Garrett Williams, who saw full participation in practice for the first time this season on Friday. He is on track to make his season debut after tearing his Achilles last December.

Getting Williams back is huge for a Cardinals secondary that was dealt tough injury news this week as cornerback Will Johnson was placed on injured reserve with a potentially season-ending neck injury.

Quarterback Jacoby Brissett remained on the injury report with a hip issue, but he was a full participant in all three days of practice.

While Arizona’s secondary is reeling, San Francisco’s receiving corps is having its own injury problems.

Receivers De’Zhaun Stribling, Ricky Pearsall and Christian Kirk are already on injured reserve, while Mike Evans is questionable and Demarcus Robinson was ruled out for Sunday.

Here is the final injury report for the Cardinals’ Week 3 game against the 49ers:

Cardinals-49ers Week 3 injury report

Arizona Cardinals
Player Pos Injury Wednesday Thursday Friday Game Status
Isaac Seumalo OL NIR-Rest DNP Full — —
Josh Sweat LB NIR-Rest DNP Full — —
Roy Lopez DL Groin DNP DNP Limited Questionable
Max Melton CB Toe DNP Limited Limited Questionable
Dadrion Taylor-Demerson S Back DNP Limited DNP Out
Garrett Williams CB Achilles Limited Limited Full —
Hjalte Froholdt OL Knee Limited Limited Full —
Mack Wilson Sr. LB NIR-Rest/Thumb Limited Full Full —
Jacoby Brissett QB Hip Full Full Full —

San Francisco 49ers
Player Pos Injury Wednesday Thursday Friday Game Status
Nick Bosa DE NIR-Rest/Knee DNP DNP DNP Out
Mike Evans WR Hip DNP DNP Limited Questionable
Dre Greenlaw LB NIR-Rest/Achilles DNP Full Full —
Romello Height DE Hand DNP DNP DNP Out
Christian McCaffrey RB NIR-Rest DNP Full Full —
Demarcus Robinson WR Ankle DNP DNP DNP Out
James Thompson DT Ankle DNP DNP DNP Out
Trent Williams T NIR-Rest DNP Full Full —

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Comments

2 Comments

T
The Skyhawk 1 day ago

Sweat is a little B. F him.

J
James Bondage 1 day ago

Sure glad Sweat is getting all that rest!