Houston-Arizona Sweet 16 betting odds: Wildcats slim favorites

Mar 24, 2022, 1:25 PM
Fabian White Jr. #35 and Kyler Edwards #11 of the Houston Cougars react after defeating the Illinoi...
Fabian White Jr. #35 and Kyler Edwards #11 of the Houston Cougars react after defeating the Illinois Fighting Illini 68-53 during the second round of the 2022 NCAA Men's Basketball Tournament at PPG PAINTS Arena on March 20, 2022 in Pittsburgh, Pennsylvania. (Photo by Kirk Irwin/Getty Images)
(Photo by Kirk Irwin/Getty Images)

The analytic models really like the No. 5 seed Houston Cougars, even against the No. 1 seed in their NCAA Tournament region. has them as the 10th-best team on offense and defense for the season, and ESPN’s Basketball Power Index has the Cougars with a 60.5% chance of beating the No. 1 seed Arizona Wildcats in their Sweet 16 matchup in San Antonio on Thursday night.

It would not be a shock to see the Cougars upset the 33-3 Wildcats, ending their NCAA Tournament run under first-year coach Tommy Lloyd.

Not helping matters is their recent play: Houston comes off a 15-point win against Illinois, while Arizona needed overtime to hold off a pesky TCU Horned Frogs team in the round of 32 on Sunday.

The odds match up with what could be a toss-up.

Arizona remains a 1.5-point favorite the morning of gameday, according to the FanDuel sportsbook.

The over/under sits at 146.5, while the moneyline sits at -134 for Arizona and +112 for Houston.

The South Region matchup hast the second-closest odds in the Sweet 16. Only No. 2 seed Duke Blue Devils and No. 3 seed Texas Tech Red Raiders have slimmer odds, with the latter team being the favorite.

Upstarts Saint Peter’s, a No. 15 seed, faces the longest odds as 12.5-point underdogs against the No. 3 seed Purdue Boilermakers.

The only other double-digit matchup is No. 1 overall seed Gonzaga Bulldogs, who are 10-point favorites over the No. 4 seed Arkansas Razorbacks.

Arizona Basketball

Azuolas Tubelis #10 of the Arizona Wildcats moves the ball up-court past head coach Tommy Lloyd dur...
Arizona Sports

Report: Arizona, Alabama hoops finalizing neutral site game in Phoenix

The Arizona Wildcats and Alabama Crimson Tide men's basketball teams are finalizing a game at Footprint Center, reports Jon Rothstein.
3 days ago
Florida Atlantic players celebrate after defeating Kansas State in an Elite 8 college basketball ga...
Associated Press

Florida Atlantic punches ticket to Final Four with upset win over Kansas State

Florida Atlantic had never won an NCAA Tournament game prior to this season. Now in its second-ever tourney trip, FAU is Final Four bound.
5 days ago
TUCSON, ARIZONA - DECEMBER 22: Adama Bal #2 of the Arizona Wildcats handles the ball against Khalil...
Austin Scott

Adama Bal leaving Wildcats via transfer portal

Sophomore guard Adama Bal marks the second Arizona Wildcat to enter the transfer portal, after averaging 2.5 points per game off the bench.
7 days ago
Arizona guard Kerr Kriisa (25) reacts after Arizona State guard Desmond Cambridge Jr. hits a three ...
Arizona Sports

Kerr Kriisa entering transfer portal after 3rd year with Wildcats

Point guard Kerr Kriisa will enter the transfer portal after playing his third year with the Arizona Wildcats, he told ESPN.
8 days ago
Lauren Fields #23 of the Arizona Wildcats shoots as Abby Meyers #10 of the Maryland Terrapins defen...
Associated Press

Arizona WBB eliminated from NCAA Tournament with loss to No. 2 seed Maryland

Diamond Miller scored 24 points to help Maryland to a 77-64 victory over Arizona in the second around of the NCAA Tournament on Sunday night.
11 days ago
Arizona Wildcats guard Lauren Fields (23) shoots over West Virginia Mountaineers forward Isis Beh (...
Arizona Sports

March Madness: Arizona WBB underdogs in 2nd-round matchup with Maryland

Arizona women's basketball is the final of four teams from the state alive in March Madness after defeating West Virginia 75-62 on Friday. 
12 days ago
Houston-Arizona Sweet 16 betting odds: Wildcats slim favorites