49ers-Cardinals injury update: Kyler Murray, DeAndre Hopkins questionable for MNF

Nov 19, 2022, 4:15 PM | Updated: 4:16 pm

Kyler Murray...

Kyler Murray #1 of the Arizona Cardinals looks on during warmups prior to the game against the Los Angeles Rams at SoFi Stadium on November 13, 2022 in Inglewood, California. (Photo by Sean M. Haffey/Getty Images)

(Photo by Sean M. Haffey/Getty Images)

The Arizona Cardinals’ injury report for a crucial Week 11 matchup with the San Francisco 49ers included a hamstring issue popping up for star wide receiver DeAndre Hopkins that kept him limited on Friday.

Head coach Kliff Kingsbury called it a “maintenance issue,” a sign Hopkins should be ready to play on Monday Night Football.

Hopkins, though, was ruled questionable on Saturday’s injury report that included game statuses. Quarterback Kyler Murray was also ruled questionable.

Murray (hamstring) practiced in a limited fashion while backup Colt McCoy (knee) was a full participant on Friday after both were limited the day prior. Murray did the same last week before not playing while McCoy’s knee injury in the game only shortly kept him sidelined before he finished it out. Murray and Hopkins were limited on Saturday’s estimated injury report.

Kingsbury ruled out starting left tackle D.J. Humphries (back), who will be replaced again by Josh Jones.

In addition, No. 1 cornerback Byron Murphy Jr. was ruled out Saturday after not participating all week with a back issue. Pro Bowl safety Budda Baker played through an ankle injury on Sunday and did not have a game status listed Saturday, so he is good to go.

Kicker Matt Prater (right hip/illness) is also set to play Monday.

For San Francisco, defensive lineman Arik Armstead (foot/ankle) remains out, while DL Samson Ebukam (quadricep/Achilles) is questionable. Armstead has played in just three games and Ebukam missed his first game last week.

The full injury report is below:

49ers vs. Cardinals injury report


Player Position Injury Thursday Friday Saturday Game Status
Budda Baker S Ankle DNP Limited Full
Zach Ertz TE Knee DNP DNP DNP Out
DeAndre Hopkins WR Hamstring DNP Limited Limited Questionable
D.J. Humphries OL Back DNP DNP DNP Out
Byron Murphy Jr. CB Back DNP DNP DNP Out
Max Garcia OL Shoulder Limited Limited Limited Questionable
Markus Golden LB Illness Limited Full Full
Colt McCoy QB Knee Limited Full Full
Kyler Murray QB Hamstring Limited Limited Limited Questionable
Matt Prater K Right Hip/Illness Full Full Full


Player Position Injury Thursday Friday Saturday Game Status
Arik Armstead DT Foot/Ankle DNP DNP DNP Out
Nick Bosa DE NIR-Rest DNP Full Full
Samson Ebukam DE Quadriceps/Achilles DNP Limited Limited Questionable
Charvarius Ward CB NIR-Personal DNP DNP Full
Trent Williams T NIR-Rest DNP Full Full
Danny Gray WR Ankle Limited Full Full

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Western Governors University


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Injury Report is presented by: Arizona Department of Health Services

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